This observational study, called "Genetic Investigation of Cancer Predisposition," aims to understand why some people develop cancer by looking for specific genetic changes. Researchers will collect clinical information and samples like blood, saliva, and tumor tissue from people with multiple cancers or a family history of cancer. They will use DNA or RNA sequencing to identify rare genetic changes that might be linked to cancer. The study will also look for these genetic changes in family members. The goal is to find rare genetic variants and tumor-specific mutations. This study is open to people of all ages who have a personal history of cancer before age 50, more than one primary cancer, or cancer with a family history that doesn't fit typical hereditary cancer patterns. The current status of this study is unclear.

Study design

This is an observational study that plans to enroll 100 participants. It is not a treatment study, but rather aims to understand genetic factors related to cancer.

What's involved

You would provide clinical information and samples such as blood, saliva, and tumor tissue. These samples will be used for genetic sequencing.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoints, such as identifying genetic variants, will be measured through study completion, which is approximately 6-12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.