This study aims to understand how kidney cancers, including renal cell carcinomas and urothelial cell carcinomas, use different nutrients to grow. Researchers will give participants an infusion of a specially labeled nutrient (13C-Glucose, 13C-Acetate, 13C-Lactate, 13C-Glutamine, or 13C-Fructose) for 2-3 hours before surgery or biopsy. These nutrients are common and not harmful. During the infusion, blood samples will be taken every 30 minutes. After surgery, a tissue sample will be collected. This allows researchers to track how cancer cells use these nutrients. The study is looking for 600 participants aged 18 or older with kidney or urothelial cancer needing surgery or biopsy. The main goal is to measure how these labeled nutrients are used by the cancer cells over 5 years.

Study design

This is an interventional study with a planned enrollment of 600 participants. It is not specified if it's randomized or blinded.

What's involved

You would receive an intravenous (IV) infusion of a labeled nutrient for 2-3 hours before surgery or biopsy. Blood samples will be collected approximately every 30 minutes during the infusion.

Compensation

Not stated in the trial record.

Follow-up

The study will measure the use of labeled nutrients by cancer cells for 5 years after the initial procedure.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.