Hyperpolarized 129Xe MR Imaging for Lung Function
This study is looking at a special type of MRI using hyperpolarized 129Xe gas to better understand lung function. We want to see if this imaging method can help doctors assess lung health in people with conditions like asthma, COPD, cystic fibrosis, interstitial lung disease, and pulmonary hypertension. We are also including healthy volunteers. During the MRI, you would breathe in a small amount of hyperpolarized 129Xe gas. The main goal is to measure something called the RBC/Barrier Ratio on the first day of the study. This study is currently unclear about its recruitment status and plans to enroll about 260 participants.
- Study design
- This is an open-label study, meaning everyone knows what treatment is being given. It plans to include about 160 people with lung disease and 100 healthy volunteers.
- What's involved
- You would have one imaging session on a single day. This involves inhaling hyperpolarized 129Xe gas up to four times, plus one calibration dose, during MRI scans.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary measurement for the study, the RBC/Barrier Ratio, is taken on Day 1. No further follow-up is specified.
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Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Peter Niedbalski, PHD · PRINCIPAL_INVESTIGATOR · University of Kansas Medical Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- RBC/Barrier RatioDay 1
Ratio of xenon signal dissolved in RBCs to xenon signal dissolved in Barrier Tissues