Aria Sensor for Swallowing and Drooling in Parkinson's Disease

This study is testing a new wearable device called the Aria Sensor for people with Parkinson's disease who experience swallowing difficulties (dysphagia) and drooling (sialorrhea). The Aria Sensor is a patch that monitors your body's signals and provides gentle vibrations to help you swallow more often. You would use the sensor for three weeks, with the vibrations active only during the second week. To join, you need to be at least 22 years old, speak English, have a Parkinson's diagnosis from a neurologist, and experience mild to moderate drooling. The researchers want to see how well the sensor can detect swallowing and if it helps increase how often you swallow. The current recruitment status is unclear.

Study design
This interventional study plans to enroll 60 participants. It is focused on the early development and validation of the Aria Sensor.
What's involved
You would use the Aria Sensor over a 3-week period, with active haptic cueing during Week 2 only. You must be in the "on" phase of your medication during all study assessments.
Compensation
Not stated in the trial record.
Follow-up
The study will measure agreement with a 'Gold Standard' at 1 year, suggesting a follow-up period.

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NCT04664634

A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's

Recruiting
PHASE3Ages 22+InterventionalDiagnostic
Northwestern University
~60 participants
Updated 2026-08-24 on ClinicalTrials.gov
What's tested:Aria Sensor

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percent agreement with Gold Standard
Measured over 1 year
+1 more outcome measured
Dysphagia
Parkinson Disease
1 sites across 1 states
Illinois1

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  • Percent agreement with Gold Standard1 year

    Percent agreement between experimental sensor Gold standard (GS) respiratory inductance plethysmography (RIP) with Inductotrace System®, Ambulatory Monitoring)

  • Change in mean swallow frequency during haptic cueing weekWeek 1 to Week 2

    This outcome measures the change in the average number of swallows per hour during the intervention week (Week 2, with haptic cueing) compared to baseline (Week 1, no cueing). Swallows will be manually labeled from sensor audio recordings by at least three independent annotators.