Pain Relief After Thumb Osteoarthritis Surgery: Ibuprofen & Acetaminophen vs. Oxycodone
This study is looking at pain relief after surgery for thumb osteoarthritis (a type of arthritis at the base of the thumb). Typically, strong pain medications called opioids, like oxycodone, are used after this surgery. However, doctors are looking for ways to reduce opioid use because they can be addictive. This study compares a combination of non-opioid medications, ibuprofen and acetaminophen, to oxycodone for managing pain in the first 30 days after surgery. You may be able to join if you are 45 or older, having trapeziectomy surgery for thumb osteoarthritis, and can speak English. The study will measure how much medication you use and your daily pain levels to see which treatment works best. The current recruitment status is unclear.
- Study design
- This is an interventional study planning to enroll 121 participants. It compares two different pain medication approaches.
- What's involved
- You would take study medication daily from the first day after surgery for 30 days. You would also record your pain scores daily during this time.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 30 days after surgery to measure medication consumption and pain scores.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Amy Ladd, MD · PRINCIPAL_INVESTIGATOR · Stanford Orthopaedic Surgery
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change of medication consumption and overall amountEvery day from the first day after surgery to 30 days post-op.
The number of capsules consumed in the last 24 hours. Consumption rate and overall consumption will be compared between groups to assess efficacy and inform further statistical analyses.
- Change of worst daily pain score measured over timeEvery day from the first day after surgery to 30 days post-op.
Numerical score describing surgical pain at its worst in the last 24 hours, between 1 and 10, 1 being no pain, 10 being the worst possible pain.
- Change of least daily pain score measured over timeEvery day from the first day after surgery to 30 days post-op.
Numerical score describing surgical pain at its least in the last 24 hours, between 1 and 10, 1 being no pain, 10 being the worst possible pain.
- Change of average daily pain score measured over timeEvery day from the first day after surgery to 30 days post-op.
Numerical score describing average surgical pain in the last 24 hours, between 1 and 10, 1 being no pain, 10 being the worst possible pain.