Medrol Dose Pack for Acute Post-Concussion Headaches

This study is looking at whether a medication called Methylprednisolone (Medrol Dose Pack) can help people who have headaches after a concussion (Post-Concussion Syndrome). Researchers want to see if this medicine can reduce how often or how bad these headaches are, and if it can help with other symptoms like dizziness, allowing people to return to daily activities sooner. The study plans to enroll 25 adults, aged 18 and older, who are able to take oral medication. Success will be measured by changes in headache symptoms after one week. The current recruitment status is unclear.

Study design
This is an observational study with a planned enrollment of 25 participants. It is not specified if it is a randomized or blinded study.
What's involved
Participants will take the Methylprednisolone dose pack, which is tapered over 7 days. The study will measure changes in headaches at 1 week.
Compensation
Not stated in the trial record.
Follow-up
Headaches will be measured at 1 week after starting the medication.

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NCT04685772

Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches

Recruiting
Not specifiedAges 18+Observational
Northwell Health
~25 participants
Updated 2026-08-26 on ClinicalTrials.gov
What's tested:Methylprednisolone

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in headaches
Measured over 1 Week
Post-Concussion Syndrome
Headache
1 sites across 1 states
New York1
  • Jamie S Ullman, MD · PRINCIPAL_INVESTIGATOR · Hofstra Northwell School of Medicine

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  • Change in headaches1 Week

    Defined as change in headache in response to medication