Cervical Interbody Implant Study for Degenerative Disc Disease and Cervical Spinal Instability

This study is looking at the safety and performance of cervical spine surgery using specific interbody implants (Cohere Cervical or Modulus Cervical) in people with degenerative disc disease or cervical spinal instability. You could join if you are at least 18 years old and are planning to have cervical spine surgery using one of these implants. The study will look at how many complications happen and how well the bones fuse together after surgery, over 24 months. The study is currently unclear on its recruitment status and plans to enroll at least 150 participants.

Study design
This is an observational study that will follow at least 150 participants, with 75 in each implant group, for 24 months.
What's involved
You would undergo interbody fusion surgery using one of the specified implants as part of your surgeon's standard care.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 24 months after surgery to check for complications and fusion success.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04689854

Cervical Interbody Implant Study

Enrolling by Invitation
Not specifiedAges 18+Observational
NuVasive
~150 participants
Updated 2025-12-22 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 7 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Complications of Interbody Implants
Measured over 24 months
+1 more outcome measured
Degenerative Disc Disease
Cervical Spinal Instability

NCT04689854

Where you'd take part

This study runs at 7 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Columbia Orthopedic Group Research

    Columbia, Missourino site contact published

  • Duke University

    Durham, North Carolinano site contact published

  • Hartford Healthcare Bone and Joint Institute

    Hartford, Connecticutno site contact published

  • Mass General Brigham

    Somerville, Massachusettsno site contact published

  • Orthopedic Specialty Institute

    Orange, Californiano site contact published

  • Summa Health

    Akron, Ohiono site contact published

  • University of Virginia

    Charlottesville, Virginiano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Kyle Malone, MS · STUDY_DIRECTOR · Globus Medical

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Complications of Interbody Implants24 months

    Rate of complications (i.e., safety) attributable to the use of the interbody implants to be studied.

  • Radiographic Fusion Success24 months

    The proportion of subjects with apparent radiographic fusion (i.e., performance) of the index surgical level(s) at 24 months postoperative.