This observational study is looking at the natural history (how a disease progresses without intervention) of prostate cancer in men who have specific genetic changes. Researchers want to understand how these genetic changes, called variants, relate to how prostate cancer develops and responds to treatment. They are studying variants in genes like BRCA1, BRCA2, and others, as well as tumor mutational burden (TMB), which is a measure of how many mutations are in a tumor. You may be able to join if you are an adult male (18 or older) with prostate cancer and have certain known genetic variants. The study aims to follow the course of your prostate cancer over time to better understand these genetic links.

Study design

This is an observational study, meaning researchers will watch the natural course of the disease without providing any specific interventions. It plans to include up to 2000 participants.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The study will observe the natural history of prostate cancer with known genetic variants and TMB-H (high tumor mutational burden) on an ongoing basis.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.