Beat Childhood Cancer Specimen Banking and Data Registry

This study is creating a registry of information and banked samples from children, adolescents, and young adults with cancer or who are cancer survivors. There is no intervention or treatment being tested; it's an observational study. Researchers want to understand the connection between changes in genes (genomic alterations) and how cancer progresses. They hope to identify different types of gene changes within tumors and see how many of these changes could lead to new treatment options. The study aims to collect this information over 10 years. You can join if you have suspected or confirmed childhood cancer, are a survivor (more than 6 months off treatment), or have a related condition. The current recruitment status is unclear.

Study design
This is an observational study with a planned enrollment of 1000 participants. It is designed to collect data and specimens without any specific treatment.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary goals of the study are measured at 10 years, indicating a long-term follow-up period for data collection.

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NCT04715178

Beat Childhood Cancer Specimen Banking and Data Registry

Recruiting
Not specifiedAll AgesObservational
Giselle Sholler
~1,000 participants
Updated 2026-02-03 on ClinicalTrials.gov
What's tested:No intervention- registry only

At a glance

Recruiting sites
17 of 18 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Create a data registry of clinical and molecular/genomic data
Measured over 10 Years
+4 more outcomes measured
Pediatric Cancer
Survivorship
18 sites across 14 states
Florida3
Missouri2
North Carolina2
Arkansas1
California1
Connecticut1
Iowa1
Kentucky1
  • Giselle Sholler, MD · STUDY_CHAIR · Beat Childhood Cancer

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Eligibility criteria

Inclusion

No age restrictions
Subjects that fit into one of the following categories:
Written informed consent in accordance with institutional and FDA guidelines must be obtained from all subjects (or subjects' legal representative).

Exclusion

Subject or his/her legally authorized representative (where applicable) did not consent for specimen banking and data collection for this study.
  • Create a data registry of clinical and molecular/genomic data10 Years

    Create a data registry of clinical and molecular/genomic data from cancer patients who have undergone biopsy or surgical resection for clinical care to better understand the relationship between genomic and molecular information and clinical outcomes.

  • Determine number and types of genomic alterations within tumor types/subtypes10 Years

    Define genomic landscape of pediatric cancers through the determination of the number and types of genomic alterations within tumor types/subtypes, across tumor types, and tumor evolution over time.

  • Evaluate the rate of actionable genomic alternations10 Years

    Evaluate the rate of actionable genomic alternations resulting in associated targeted therapies relative to all actionable genomic alterations.

  • Evaluate the correlation of baseline genomic alterations with clinical outcome.10 Years

    Evaluate the correlation of baseline genomic alterations with clinical outcome.

  • Identify biomarkers that predict risk of adverse outcomes that occur following pediatric cancer therapy.10 Years

    Identify biomarkers that predict risk of adverse outcomes that occur following pediatric cancer therapy.