Long-term Safety Study of Rimegepant for Migraine in Children and Adolescents

This study is looking at the long-term safety of rimegepant (PF-07899801), a medication for the acute treatment of migraine, in children and adolescents aged 6 to 17 years old. Researchers want to understand how often and how severely side effects occur, including serious side effects and those that lead to stopping the medication. They will also look for any significant changes in lab test results. You may be able to join if you have a history of migraine for at least 6 months, experience 1 to 8 moderate or severe migraine attacks per month, and need treatment for migraines. The study plans to enroll 600 participants, but its current recruitment status is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It aims to enroll 600 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for adverse events and lab abnormalities for 58 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04743141

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

Recruiting
PHASE3Ages 6–17InterventionalTreatment
Pfizer
~600 participants
Updated 2026-08-14 on ClinicalTrials.gov
What's tested:Rimegepant (PF-07899801)

At a glance

Recruiting sites
67 of 124 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The frequency and severity of on-treatment and treatment-emergent adverse events, serious adverse events, adverse events leading to discontinuation, clinically significant lab abnormalities
Measured over 58 weeks
Acute Treatment of Migraine
124 sites across 36 states
California14
Texas14
New York8
Colorado7
Florida7
Virginia6
Poland6
Michigan5
  • Pfizer CT.gov Call Center · STUDY_DIRECTOR · Pfizer

Opens a ready-to-send draft in your own email app — review before sending.

  • The frequency and severity of on-treatment and treatment-emergent adverse events, serious adverse events, adverse events leading to discontinuation, clinically significant lab abnormalities58 weeks

    To evaluate the safety and tolerability of rimegepant in children and adolescents (6 to \< 18 years of age).