Food and Circadian Timing Study
This study aims to understand how different diets affect your body's internal clock, called the circadian rhythm. Researchers will compare a High-Fat Diet and a Low-Fat Diet to see how each impacts the speed at which your body adjusts to a new schedule. They hope to learn if diet plays a role in how well your body's clock stays in sync with the 24-hour day. You may be able to join if you are a healthy, lean man or woman between 18 and 40 years old. The study is looking to enroll 14 participants, but its current recruitment status is unclear.
- Study design
- This is a randomized crossover study involving 14 participants. This means participants will receive both the High-Fat Diet and the Low-Fat Diet at different times.
- What's involved
- You would participate for a total of 46 days, including 28 days as an outpatient and two separate 9-day stays in a clinic.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome, change in speed of entrainment, is measured over 18 days.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Food and Circadian Timing
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Andrew McHill, PhD · PRINCIPAL_INVESTIGATOR · Oregon Health and Science University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in Speed of entrainmentOver 18 days
Entrainment will be determined as a stable phase angle between sleep and both melatonin onset. Blood and/or saliva will be assayed for melatonin using standardized assays. Melatonin onset will be calculated using the linear interpolated time at which melatonin levels reach 25% of a fitted peak-to-trough amplitude. This will be analyzed using phase angle between sleep and melatonin onset.