Anti-inflammatory Diet for Rheumatoid Arthritis

This study is looking at whether adding an anti-inflammatory diet can help people with rheumatoid arthritis (a condition causing joint pain and swelling). Researchers want to see if this diet improves symptoms and how it might affect your gut bacteria (microbiome) and other substances in your blood. You might be able to join if you have low to moderate rheumatoid arthritis activity, haven't changed your treatment in the last three months, and are interested in trying a special diet. The study will consider the diet successful if participants see a decrease of more than 5 points in their Clinical Disease Activity Index (a measure of disease activity) after 3 months. The current status of this study is unclear.

Study design
This interventional study plans to enroll 124 participants. It compares two different dietary interventions.
What's involved
You would need to be interested in a dietary intervention, provide consent, and attend follow-up visits.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured at 3 months, suggesting follow-up for at least this duration.

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NCT04748809

Effect of Anti-inflammatory Diet in Rheumatoid Arthritis

Recruiting
NAAges 18+InterventionalSupportive care
University of California, San Diego
~124 participants
Updated 2026-01-09 on ClinicalTrials.gov
What's tested:Diet 1Diet 2

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Decrease of more than 5 points in Clinical Disease Activity Index
Measured over 3 months
Rheumatoid Arthritis
1 sites across 1 states
California1

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Eligibility criteria

Inclusion

Patients with low or moderate disease activity (defined as Clinical Disease Activity Index ≤ 22) and without changes in disease activity or therapy during the previous 3 months, who are interested in dietary intervention, and are able to provide consent and attend to follow up visits.

Exclusion

Pregnancy or lactating. Patients that will become pregnant during the study will be remove from the study.
Food allergies
Subjects with significant other comorbidities and /or medication use which in physician's clinical judgment might difficult the interpretation of the results
  • Decrease of more than 5 points in Clinical Disease Activity Index3 months