BreEStim for Post-Stroke Motor Recovery

This study is looking at how well a new treatment called BreEStim, which is a type of breathing-controlled electrical stimulation, can help people who have had a stroke. Researchers want to see if BreEStim can reduce stiffness in finger muscles (spasticity) and improve hand function. You might be able to join if you are between 18 and 75 years old, had a stroke at least 6 months ago, and have some finger stiffness. People with certain vision, hearing, or thinking problems, or a history of lung disease, cannot participate. The study will measure changes in finger stiffness shortly after the treatment. The current status of this study is unclear.

Study design: This is an interventional study with a planned enrollment of 4 participants. It compares BreEStim with EStim (electrical stimulation).
What's involved: BreEStim or EStim will be applied for 10 to 20 minutes.
Compensation: Not stated in the trial record.
Follow-up: Your finger stiffness will be measured at the start and 5 minutes after the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

BreEStim for Post-Stroke Motor Recovery

Recruiting

NAAges 18–75InterventionalTreatment

The University of Texas Health Science Center, Houston

~4 participants

Updated 2026-06-03 on ClinicalTrials.gov

What's tested:BreEStimEStim

At a glance

Recruiting sites

1 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Change in finger flexor spasticity measured by Modified Ashworth Scale (MAS)

Measured over Baseline, 5 minutes after intervention

Conditions

Motor Recovery

Where it's being run

1 sites across 1 states

Texas1

Study leadership

Sheng Li, MD, PhD · PRINCIPAL_INVESTIGATOR · University of Texas

Who to contact

Sheng Li, MD, PhD

[email protected]

(713) 797-7125

Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

has post stroke ≥ 6 months , medically stable;

Unilateral, single stroke (no restriction on type (ischemic or hemorrhagic) or volume (large or small) of stroke);

MAS score ≥ 1, i.e., detectable finger flexor hypertonia;

Exclusion

Patients with visual deficit/neglect; hearing or cognitive impairment;

Patients with history of pulmonary disease (Asthma, chronic obstruction pulmonary disease, COPD);

Patients that are currently adjusting tone alternating medications (e.g., baclofen), or

Patients received botulinum toxin injection to the arm/fingers \<4 months, or phenol injections \< 2 years;

Patients with a pacemaker;

Women who are pregnant.

What this trial measures

Change in finger flexor spasticity measured by Modified Ashworth Scale (MAS)Baseline, 5 minutes after intervention
MAS will be performed to check changes of finger flexor spasticity after one session of treatment. The Modified Ashworth scale (MAS) scoring is categorical and ranges from 0 to 4, as follows: 0: No increase in muscle tone 1. Slight increase in muscle tone, manifested by a catch and release or by minimal resistance at the end of the range of motion when the affected part(s) is moved in flexion or extension 1+: Slight increase in muscle tone, manifested by a catch, followed by minimal resistance throughout the remainder (less than half) of the range of motion (ROM) 2. More marked increase in muscle tone through most of the ROM, but affected part(s) easily moved 3. Considerable increase in muscle tone, passive movement difficult 4. Affected part(s) rigid in flexion or extension

Trialytics