COLON-MD: Colon Cancer Longitudinal Study
This observational study aims to understand how your gut microbiome (the collection of tiny organisms in your intestines) and diet affect chemotherapy-induced diarrhea in people with colon cancer. Researchers will collect samples of your gut microbiome, diet information, and blood samples before your colonoscopy or surgery. They will then use this information to predict if you will experience diarrhea from chemotherapy and how severe it might be. The study is looking for about 11 participants aged 18 to 79 who have been diagnosed with colon cancer and are expected to receive FOLFOX chemotherapy. The study's success will be measured by its ability to predict chemotherapy-induced diarrhea based on microbiome and diet over three years. The current recruitment status is unclear.
- Study design
- This is an observational study with a planned enrollment of 11 participants. It is a longitudinal study, meaning participants will be followed over time.
- What's involved
- You would provide samples of your gut microbiome, dietary intake information, and blood samples. These samples would be collected prior to your scheduled colonoscopy or surgery.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for three years to measure microbiome-based prediction of chemotherapy-induced diarrhea.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
COLON-MD: Colon Cancer Longitudinal Study
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Inclusion
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What this trial measures
- Microbiome-Based Prediction of Chemotherapy-induced Diarrhea in Colon Cancer3 years
Microbiome analysis from at least 112 blinded samples will be conducted from fecal samples to determine sensitivity, specificity and accuracy (reported as percentage) of a microbiome-based predictor of chemotherapy-induced diarrhea in colon cancer.