This study is looking at how electroconvulsive therapy (ECT) affects the brain's electrical activity and structure. Researchers will use special brain scans (fMRI and structural MRI) to understand these changes. You might be able to join if you are between 18 and 80 years old, have certain positive symptoms like hallucinations or unusual thoughts, and have not responded to at least one antipsychotic medication. The study will measure how much your symptoms improve using a scale called the Brief Psychiatric Rating Scale (BPRS) over 8 weeks. The current recruitment status is unclear.

Study design

This study will include 75 participants and will follow them over time to see how electroconvulsive therapy affects their brains and symptoms.

What's involved

You would have weekly monitoring with the Brief Psychiatric Rating Scale (BPRS) and undergo structural and functional MRI and MATRICS battery testing before and at the end of the study.

Compensation

Not stated in the trial record.

Follow-up

You will be followed up until your 8th week of electroconvulsive therapy clinically, with primary and secondary measures taken at baseline and 8 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.