High Frequency Ventilation for Congenital Diaphragmatic Hernia
This study is looking at two different ways to help babies with congenital diaphragmatic hernia (CDH) breathe: High Frequency Jet Ventilation (HFJV) and High Frequency Oscillatory Ventilation (HFOV). Both are standard methods used in the NICU (Neonatal Intensive Care Unit). Researchers want to see which method works better for these babies by comparing how well their oxygen levels are at 24 hours of age. Babies who are 24 hours old or less, need a breathing machine, and have an arterial line can join. You cannot participate if your baby has severe chromosomal abnormalities. The study plans to include 50 babies, but the current recruitment status is unclear.
- Study design
- This study is an interventional study that will randomize 50 participants to receive either High Frequency Jet Ventilation or High Frequency Oscillatory Ventilation.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, Oxygenation Index, is measured at 24 hours of age.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia
At a glance
Conditions
Where it's being run
2 sites across 1 statesStudy leadership
- Michelle Yang, MD · PRINCIPAL_INVESTIGATOR · University of Utah
Who to contact
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What this trial measures
- Oxygenation Index (OI) at 24 hours of age24 hours of age
The OI will be measured at 24 hours of age using a standard of care arterial blood gas and oxygen settings. These measurements will then be compared between the stratified groups