This study is looking at how the bacteria, fungi, and viruses (your microbiome) in your gut and urine change during prostate cancer treatment. Specifically, it focuses on patients receiving androgen deprivation therapy (hormone therapy) and radiation therapy for Stage I, II, or III prostate cancer. Researchers want to see if these microbiome changes might affect how your body heals after radiation, which can sometimes cause issues in the bladder or bowel. You would provide urine and stool samples and complete questionnaires about your quality of life. The main goal is to see if it's possible to track these microbiome changes, and a secondary goal is to explore if your microbiome at the start of treatment is linked to any side effects you might experience.

Study design

This is an observational study, meaning no new treatments are given. It plans to enroll 30 men with prostate cancer.

What's involved

You would provide stool and urine samples at different times before, during, and after your treatment. You will also complete questionnaires and your medical records will be reviewed.

Compensation

Not stated in the trial record.

Follow-up

You would be followed for up to 3 years after completing radiation therapy.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.