This study is looking for people aged 18 or older who are on the lung transplant waiting list at Duke University Medical Center and have pulmonary hypertension (high blood pressure in the lungs) due to interstitial lung disease (scarring of the lungs) or COPD (chronic obstructive pulmonary disease). The goal is to find a unique pattern using hyperpolarized 129Xe (xenon gas) magnetic resonance imaging (129Xe MRI) that shows how blood vessels in the lungs are changing. This pattern could help doctors identify which patients with Group 3 pulmonary hypertension might benefit from specific treatments. The study aims to see if this pattern matches changes seen in lung tissue after transplant. This research could help predict how patients will respond to treatments in the future.

Study design

This interventional study plans to enroll 30 participants. It is not specified if it is randomized or blinded.

What's involved

Participants will receive a dose of hyperpolarized 129Xe gas for the MRI. The primary endpoint is measured at Day 1.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint is measured at Day 1, but further follow-up is not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.