Quality of Life and Lifestyle Factors in Melanoma Patients

This observational study is looking at how lifestyle factors like mental health, social support, diet, and exercise are connected to the quality of life and outcomes for people with melanoma. Researchers will review your medical charts and ask you to complete questionnaires. The goal is to understand how these factors relate to changes in depression, anxiety, and cancer-related symptoms over a period of up to 10 years. This information could help doctors better advise melanoma patients in the future. The study aims to enroll 5000 participants.

Study design
This is an observational study, meaning researchers will collect information without giving any specific treatments. It plans to include 5000 participants.
What's involved
You would complete up to three paper or electronic questionnaires, each taking about 30 minutes, at specific times related to your diagnosis or treatment. You might also complete an additional dietary questionnaire or a phone-based dietary recall.
Compensation
Not stated in the trial record.
Follow-up
Researchers will look at changes in depression, anxiety, and cancer-related symptoms for up to 10 years.

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NCT04778449

Quality of Life, Lifestyle, and Psychosocial Factors in Patients With Melanoma

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~5,000 participants
Updated 2026-05-05 on ClinicalTrials.gov
What's tested:Medical Chart ReviewQuestionnaire Administration

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in depression/distress
Measured over Up to 10 years
+9 more outcomes measured
Cutaneous Melanoma
1 sites across 1 states
Texas1
  • Carrie Daniel-MacDougall · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Diagnosis of melanoma, precursor lesions, and associated cutaneous pathology
Able to read and understand English
Willing to complete an online or paper survey
  • Change in depression/distressUp to 10 years

    Will be assessed using the Centers for Epidemiologic Studies - Depression. Lifetime history of Major Depressive Disorder (MDD) will be measured using the two cardinal items from the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-IV Disorder. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

  • Change in anxietyUp to 10 years

    Will be assessed using the Speilberger State/Trait Anxiety Inventory. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

  • Change in cancer-related symptomsUp to 10 years

    Will be assessed using the MD Anderson Symptom Inventory. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

  • Change in social supportUp to 10 years

    Will be assessed using the 24-item Social Provisions Scale. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

  • Change in general eating habitsUp to 10 years

    Will be assessed using the National Cancer Institute National Health and Nutrition Examination Survey Dietary Screener Questionnaire, and optionally, the National Institutes of Health Automated Self-Administered 24-hour.

  • Change in physical activityUp to 10 years

    Will be assessed using the Godin Leisure -Time Exercise Questionnaire. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

  • Associations between mental health, social support, diet and exercise behaviors, and quality of life and demographic variablesUp to 10 years

    Will be evaluated using Pearson's product moment correlation coefficients together with scatterplots where appropriate.

  • Effect of diet, physical activity, depressive symptoms, distress, lifetime MDD, and social support on progression free survivalUp to 10 years

    Will be evaluated using Pearson's product moment correlation coefficients together with scatterplots where appropriate.

  • Effect of diet, physical activity, depressive symptoms, distress, lifetime MDD, and social support on cancer mortalityUp to 10 years

    Will be evaluated using Pearson's product moment correlation coefficients together with scatterplots where appropriate.

  • Response to treatmentUp to 10 years

    Logistic regression models will be used to measure the association of diet, physical activity, diet, depressive symptoms, distress, lifetime MDD, and social support and response to treatment at each time point.