Epidural Stimulation and Resistance Training After Spinal Cord Injury
This study is looking at new ways to help people with spinal cord injuries (SCI) to walk again. It combines "lumbosacral epidural stimulation" (ES), which uses a device to stimulate nerves in the spinal cord, with either "Exoskeletal assisted walking" (using a robotic suit) or "Resistance Training" (exercises to build muscle). Some participants will also receive a delayed start to ES or a "no-Resistance training" program (passive movement or stretching). The study wants to see how these interventions affect your walking speed over 10 meters and your muscle electrical activity (EMG Pattern). You may be able to join if you are 18-60 years old, have a complete SCI at T10 or above, and your knee muscles respond to electrical stimulation. The study plans to enroll 20 participants, but its current status is unclear.
- Study design
- This is an interventional study planning to enroll 20 participants. It compares different combinations of epidural stimulation, exoskeletal walking, and resistance training.
- What's involved
- Participants will undergo 12 weeks of seated leg extension exercise followed by sit-to-stand exercises, or 24 weeks of passive movement/stretching. Some will use an exoskeletal device or receive epidural stimulation.
- Compensation
- Not stated in the trial record.
- Follow-up
- Changes in walking speed and EMG patterns will be measured from the beginning of the study up to 12 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Epidural Stimulation and Resistance Training After SCI
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Ashraf S Gorgey, PhD · PRINCIPAL_INVESTIGATOR · Virginia Commonwealth University
Who to contact
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What this trial measures
- Change in 10-meter over ground walking-speedBaseline to 12 months
The investigators will measure the speed of walking and the time elapsed during 10 meter distance.
- Change in EMG PatternBaseline to 12 months
The investigators will record muscle activity from the major lower extremity muscle groups.