Intraoperative Optical Coherence Tomography - Normals

This study is looking at a non-invasive imaging test called Optical Coherence Tomography (OCT) to see if new versions of this technology can improve how doctors detect eye diseases. OCT uses light waves to take detailed pictures of the back of your eye (retina). Researchers want to test these new OCT technologies on healthy adults to make sure they work well before using them in patients with eye conditions. The goal is to make OCT imaging faster and clearer to help doctors diagnose eye diseases more accurately. This is an observational study, meaning you won't receive any treatment, and it aims to enroll 20 healthy volunteers.

Study design
This is an observational study that plans to enroll 20 healthy adult volunteers. It is not specified if it is randomized or blinded.
What's involved
You may be asked to participate in optional follow-up imaging sessions for an average of 2 years.
Compensation
Not stated in the trial record.
Follow-up
You may have optional follow-up imaging for an average of 2 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04790890

Intraoperative Optical Coherence Tomography - Normals

Enrolling by Invitation
Not specifiedAges 18+Observational
Vanderbilt University Medical Center
~20 participants
Updated 2026-03-10 on ClinicalTrials.gov
What's tested:Optical coherence tomography (OCT)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Novel Ophthalmic Diagnostics using Optical Coherence Tomography
Measured over Subjects enrolled in the study may periodically be asked to participate in follow-up imaging during the duration of the study. These follow-up sessions will be optional through study completion, an average of 2 years.
Healthy Volunteers
1 sites across 1 states
Tennessee1

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Healthy adults (\>18 years) with no pre-existing ophthalmic conditions

Exclusion

Children or adults unable to consent
Any volunteers with history of ocular disease/injury
  • Novel Ophthalmic Diagnostics using Optical Coherence TomographySubjects enrolled in the study may periodically be asked to participate in follow-up imaging during the duration of the study. These follow-up sessions will be optional through study completion, an average of 2 years.

    This study will develop novel OCT technology for improved diagnostic sensitivity in ophthalmology. Specifically, we will develop novel OCT imaging and image-processing methods to improve imaging speed and quality. Successful completion of this project will improve clinical diagnostics of ophthalmic diseases. Pre-clinical validation of system performance and ergonomics is a valuable step is clinical imaging technology development. We will evaluate imaging performance for system iterations on next-generation ophthalmic OCT imaging technologies over current-generation imaging systems on healthy adult volunteers prior to clinical translation. While system resolution, contrast, and speed can be (and will be) evaluated using calibration standards and phantoms, in vivo human imaging in healthy subjects is necessary to establish a baseline for system performance and image quality prior to clinical translation.