Exercise for Diabetic Foot Ulcer Healing

This study is looking at how a structured exercise program, given through a medically supervised cardiac rehabilitation program, affects the healing of diabetic foot ulcers (DFUs). You may be able to join if you have type 2 diabetes, are between 20 and 80 years old, and have a DFU that is WIfI Grade 2 or less (a system for classifying wound severity). Your blood sugar levels (HbA1c and blood glucose) and ankle-brachial index (ABI) or toe pressure (TcPO2) will also be checked. The main goal is to see if exercise helps wounds close faster, specifically by measuring the time it takes for the wound to heal completely. The study aims to enroll 60 participants.

Study design
This study uses a two-group design where 60 volunteers will be randomly assigned to either receive standard wound care or standard wound care plus a structured exercise program.
What's involved
If you are in the exercise group, you will participate in 2-3 exercise sessions per week over a 12-week period. All participants will continue to receive their regularly scheduled standard wound care.
Compensation
Not stated in the trial record.
Follow-up
Wound healing time is measured at 12 weeks or less, indicating follow-up during this period.

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NCT04791449

Exercise Enhances Wound Healing in Patients With Diabetic Foot Ulcers

Recruiting
NAAges 20–80InterventionalTreatment
University of New Mexico
~60 participants
Updated 2026-06-11 on ClinicalTrials.gov
What's tested:Structured exercise program

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
wound healing time
Measured over 12 weeks or less
Diabetic Foot Ulcer
1 sites across 1 states
New Mexico1
  • Eric J Lew, DPM · PRINCIPAL_INVESTIGATOR · University of New Mexico Health Sciences Center

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Eligibility criteria

Inclusion

diagnosis of type 2 diabetes
20 - 80 years of age
Ankle-Brachial Index (ABI) \> 0.6 or Toe Pressure (TcPO2) \> 40 mmHg
recent (within 12 weeks) blood glucose value between 100 - 350 mg/dL
recent (within 12 weeks) HbA1c value \< 14 %,
DFU of WIfI Grade 2 or less
fluency in reading and speaking English or Spanish.

Exclusion

inability to provide own consent
inability to obtain permission to participate from a medical professional
lack of consistent mode of transportation to UNMH
infection to any part of the body
patients that has had a transplant and/or is immunocompromised
prisoners.
  • wound healing time12 weeks or less

    number of days from enrollment required to reach the maturation phase of the wound healing cascade (wound closure without drainage)