This observational study, called USOPTIVAL, is collecting blood samples and health information from people to help improve a diagnostic test. The test, called Optimization of Plasma Circulating Free-DNA (cfDNA) Marker Panel, looks for signs of colorectal cancer (CRC) and advanced adenomas (AA), which are growths that can become cancer. We are looking for people aged 45 to 84. You might be able to join if you have a suspected advanced adenoma or newly diagnosed CRC that hasn't been removed yet, or if you are scheduled for a routine colonoscopy. The main goal is to collect samples to test the cfDNA marker panel. The study is currently recruiting participants.

Study design

This is an observational study aiming to enroll 1300 participants. It is not a treatment study, but rather collects information and samples.

What's involved

If you join, you will provide up to 40 ml of blood at a study visit. You will also provide clinical data.

Compensation

Not stated in the trial record.

Follow-up

Samples will be collected for testing within 12 months of sample collection.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.