This observational study is looking for children and adults aged 5 to 100 years old who have cystic fibrosis (CF) or non-CF bronchiectasis (a lung condition where airways are damaged and widened). The goal is to find new ways to measure how severe lung disease is, how it progresses, and how well treatments work, using special MRI scans. Researchers will use Xenon gas during MRI scans to see how air moves in your lungs, and another type of MRI (UTE MRI) to look at lung structure. They believe these imaging methods can show changes in your lungs even before standard breathing tests do. The study plans to enroll 100 participants, but the current recruitment status is unclear.

Study design

This is an observational study with a planned enrollment of 100 participants. It is not a treatment study, but rather aims to understand lung disease better.

What's involved

Participants will undergo annual 129Xe and UTE MRI scans, spirometry (breathing tests), and lung clearance index (LCI) measurements for up to 5 years.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed annually for 5 years to measure the correlation of ventilated volume predictions.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.