Exercise and Sleep for Cognition in Parkinson's Disease
This study is looking at how exercise rehabilitation, specifically Progressive Resistance Training (PRT), affects thinking and memory (cognition) in people with Parkinson's disease (PD). Researchers also want to see if changes in deep sleep (slow wave sleep or SWS) can predict who will benefit most from exercise. You could be eligible if you have idiopathic PD, are between 45 and 100 years old, and are on stable medications. The study aims to see if exercise improves cognition, measured by a test called Stroop inhibition, after 12 weeks. The current recruitment status is unclear.
- Study design
- This is an interventional study planning to enroll 120 participants. Participants will be randomized (like flipping a coin) to different exercise groups.
- What's involved
- Participants in the PRT group will have supervised exercise sessions 3 times a week for 12 weeks. Those who don't respond well to PRT may switch to Endurance Training for another 12 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Cognition will be measured at the start of the study and again after twelve weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Slow Wave Sleep As a Biomarker of Rehabilitation-induced Cognitive Improvement in PD
At a glance
Conditions
NCT04796506
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Colorado, Anschutz Medical Campus
Aurora, Coloradostudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Amy Amara, MD, PhD · PRINCIPAL_INVESTIGATOR · University of Colorado, Denver
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Change in Cognition in Stroop inhibitionBaseline to twelve weeks
Change in executive function on the Stroop inhibition