Exercise and Sleep for Cognition in Parkinson's Disease

This study is looking at how exercise rehabilitation, specifically Progressive Resistance Training (PRT), affects thinking and memory (cognition) in people with Parkinson's disease (PD). Researchers also want to see if changes in deep sleep (slow wave sleep or SWS) can predict who will benefit most from exercise. You could be eligible if you have idiopathic PD, are between 45 and 100 years old, and are on stable medications. The study aims to see if exercise improves cognition, measured by a test called Stroop inhibition, after 12 weeks. The current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 120 participants. Participants will be randomized (like flipping a coin) to different exercise groups.
What's involved
Participants in the PRT group will have supervised exercise sessions 3 times a week for 12 weeks. Those who don't respond well to PRT may switch to Endurance Training for another 12 weeks.
Compensation
Not stated in the trial record.
Follow-up
Cognition will be measured at the start of the study and again after twelve weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04796506

Slow Wave Sleep As a Biomarker of Rehabilitation-induced Cognitive Improvement in PD

UNKNOWN
NAAges 45+InterventionalTreatment
University of Colorado, Denver
~120 participants
Updated 2024-10-01 on ClinicalTrials.gov
What's tested:Progressive Resistance Training (PRT)Delayed Exercise Training (DE)Endurance Training (ET)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Cognition in Stroop inhibition
Measured over Baseline to twelve weeks
Parkinson Disease

NCT04796506

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Colorado, Anschutz Medical Campus

    Aurora, Coloradostudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Amy Amara, MD, PhD · PRINCIPAL_INVESTIGATOR · University of Colorado, Denver

Opens a ready-to-send draft in your own email app — review before sending.

  • Change in Cognition in Stroop inhibitionBaseline to twelve weeks

    Change in executive function on the Stroop inhibition