Persona Revision Knee System Outcomes Study

This study is looking at how well the Persona Revision Knee System works in people who have already had knee replacement surgery. Researchers want to see if this knee system improves knee function and is safe. They will be looking at your knee score (how well your knee moves and feels) after two years. This is an observational study, meaning researchers will be watching how patients do with the Persona Revision Knee System that they already have. You can join if you are at least 18 years old and willing to follow study procedures. The study is currently unclear on its recruitment status.

Study design
This is an observational study looking at 380 patients who have already received the Persona Revision Knee System. It is a single-arm study, meaning all participants have the same intervention.
What's involved
You would be asked to participate in prospective data collection at 1, 2, 3, 4, 5, 7, and 10 years after your surgery.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 10 years after their surgery, with the primary measurement taken at 2 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04821154

Persona Revision Knee System Outcomes

Recruiting
Not specifiedAges 18+Observational
Zimmer Biomet
~380 participants
Updated 2026-07-10 on ClinicalTrials.gov
What's tested:Persona Revision Knee System

At a glance

Recruiting sites
7 of 16 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Knee Society Clinical Rating System objective knee score (KS-KS)
Measured over 2 years
Arthroplasty Complications
Infection
Knee Disease
Knee Osteoarthritis
16 sites across 13 states
Arkansas2
Indiana2
Michigan2
California1
Colorado1
Kentucky1
Minnesota1
Missouri1
  • Charles Jaggard · STUDY_DIRECTOR · Zimmer Biomet

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  • Knee Society Clinical Rating System objective knee score (KS-KS)2 years

    The primary endpoint for this study will be performance assessed by improvement in the 1989 Knee Society Clinical Rating System (KS) objective knee score (KS-KS) from baseline to 2 years (as evaluated using the overall group mean showing at least the minimal clinically important difference \[MCID\] of 5.4 points) The Knee Society objective knee score (KS-KS) assesses the knee joint by awarding points for pain, stability, and range of motion, with a minimum possible score of 0 and maximum possible score of 100. As described in Insall et al. (1989), "100 points will be obtained by a well-aligned knee prosthesis with no pain, \[at least 121\] degrees of motion, and negligible anteroposterior and mediolateral instability."