The Pediatric ALL Evaluation and Trial for ACL Injuries
This study is looking at ways to improve knee surgery for children and teenagers who have torn their anterior cruciate ligament (ACL). Researchers want to see if adding a reconstruction of another ligament, called the anterolateral ligament (ALL), at the same time as ACL reconstruction will lead to fewer problems with the ACL graft failing later on. You could be eligible if you are 18 or younger, need your first ACL surgery within 6 months of injury, and meet other specific criteria. The study aims to enroll 240 participants and will track how well the graft works for up to 5 years after surgery.
- Study design
- This is an interventional study where participants will be randomly assigned to one of two groups: either receiving both ACL and ALL reconstruction, or ACL reconstruction alone. The study plans to enroll 240 participants.
- What's involved
- Participants will receive either concomitant ACL and ALL reconstruction or ACL reconstruction alone. They will then be followed for data collection for up to 5 years.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for data collection for up to 5 years after their intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Pediatric ALL Evaluation and Trial
At a glance
Conditions
NCT04825587
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Lurie Children's Hospital
Chicago, Illinoisstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Neeraj Patel, MD · PRINCIPAL_INVESTIGATOR · Ann & Robert H Lurie Children's Hospital of Chicago
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Want this trial checked against your situation?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Graft failureComplete when all 780 participants have been recruited, received an intervention and have been followed for data collection for up to 5 years.
To determine whether concomitant ALL reconstruction in children undergoing and ACL reconstruction will longitudinally result in a lower rate of graft failure (confirmed graft re-tear or asymmetric, increased pivot shift) than ACL reconstruction alone.