Observational Study for Pediatric Rheumatologic Conditions

This observational study aims to develop a way to objectively measure pain and how well treatments work in children and young adults with Juvenile Idiopathic Arthritis (JIA), Systemic Lupus Erythematosus (SLE), and Fibromyalgia. Currently, there is no specific intervention being tested. The goal is to find a "physiologic endpoint" (a measurable body response) that could help doctors choose the best treatment more precisely, rather than using a trial-and-error approach. This study is looking for about 90 participants between 5 and 21 years old who have a confirmed diagnosis of JIA, SLE, or Fibromyalgia. Success for this study means identifying a reliable way to characterize this endpoint, which will be measured over one year.

Study design
This is an observational study, meaning there is no randomization or blinding. It aims to enroll about 90 participants.
What's involved
Patients will be followed for a period of one year after enrollment.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for one year after enrollment.

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NCT04833465

Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions

Recruiting
Not specifiedAges 5–21Observational
Children's National Research Institute
~90 participants
Updated 2026-07-24 on ClinicalTrials.gov
What's tested:No Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Index Characterization
Measured over 1 Year
Juvenile Idiopathic Arthritis
Systemic Lupus Erythematosus
Fibromyalgia
1 sites across 1 states
District of Columbia1

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Eligibility criteria

Inclusion

Male or female ≥ 5 years of age at screening.
Documentation of a JIA, SLE or FM diagnosis as evidenced by history
  • Index Characterization1 Year

    The primary objective of this study is the characterization of the nociceptive index in three pediatric rheumatology populations.