This study aims to understand how your nervous system communicates with blood vessels to raise blood pressure during stress, and how high blood pressure (hypertension) and obesity affect this process. Researchers will measure blood flow and nervous system activity in response to stress tests and an intervention called Neuropeptide Y, which is given as an intra-arterial infusion (directly into an artery). The study is looking for 100 participants, aged 18 to 55, with or without hypertension and obesity. Success will be measured by changes in blood flow and muscle sympathetic nervous system activity on the day of the study. The current recruitment status is unclear.

Study design

This is an interventional study planning to enroll 100 participants. It is not specified if it is randomized or blinded.

What's involved

You would undergo laboratory physiological stress protocols (like hypoxia or exercise) and receive infusions of drugs that affect blood vessels, including Neuropeptide Y.

Compensation

Not stated in the trial record.

Follow-up

Blood flow and muscle sympathetic nervous system activity are measured acutely on the day of the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.