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Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection

This study is looking at ways to manage pain after hepatic resection (liver surgery). Researchers want to see if adding an erector spinae plane (ESP) catheter, which delivers a local anesthetic called ropivacaine, helps reduce pain more effectively than current methods. All participants will receive spinal morphine (a pain medication given into the spine). Some will also receive a continuous infusion of 0.2% ropivacaine through an ESP catheter, while others will have a catheter taped to their skin that delivers a very small amount of ropivacaine (a placebo). The main goal is to measure how much opioid pain medication you need in the first three days after surgery. You may be able to join if you are over 18, having liver surgery, and can communicate with staff. This study is currently not recruiting.

Study design
This is an interventional study planning to enroll 70 participants. It compares two different ways of delivering pain medication after liver surgery.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your opioid use will be measured for three days after surgery, starting 24 hours after receiving spinal morphine.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04849455

Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection

Recruiting
PHASE4Ages 18+InterventionalTreatment
University of California, San Diego
~70 participants
Updated 2022-06-07 on ClinicalTrials.gov
What's tested:0.2% ropivacaine local anesthetic continuous erector spinae plane block0.2% ropivacaine local anesthetic superficially taped continuous erector spinae plane blockSpinal Morphine

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Total opioid requirement postoperative day (POD) 1-3
Measured over Total use from post-operative day (POD) 1, as defined by 24 hours after intrathecal morphine, to POD 3 (3 days from admission to recovery unit)

Conditions

Hepatic Resection
Acute Pain
Anesthesia
Anesthesia, Local

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NCT04849455

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of California, San Diego

    San Diego, Californiano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Engy T Said, MD · PRINCIPAL_INVESTIGATOR · University of California, San Diego

Who to contact

Engy T Said, MD
[email protected]
5597371904
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

undergoing hepatic resection
Admitting service requests APS consult
\>18 years old and able to provide consent

Exclusion

pregnancy
incarceration
inability to communicate with the investigators and hospital staff
severe hepatic disease
chronic high-dose opioid use (defined as daily use for more than 4 weeks prior to surgery of at least the equivalent of 20 mg oxycodone);
BMI \> 40 kg/m2
allergy to study medications (lidocaine, ropivacaine)

What this trial measures

  • Total opioid requirement postoperative day (POD) 1-3Total use from post-operative day (POD) 1, as defined by 24 hours after intrathecal morphine, to POD 3 (3 days from admission to recovery unit)

    Morphine Milligram Equivalents