Lovenox Dosing in High-Risk Pregnant Women

This study is looking at how well Lovenox (a medication to prevent blood clots) works in pregnant women who need it. Pregnancy increases the risk of blood clots, and previous studies suggest that the usual Lovenox dosing might not be enough for many pregnant women. This study will give Lovenox three times a day and measure the levels of the drug in your blood (Factor Xa levels) 4 hours after each injection. This will help researchers understand if this dosing schedule provides adequate protection. You may be able to join if you are 18 or older, are pregnant with one baby, and need Lovenox. The study is currently unclear about its recruitment status.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 12 women.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, Factor Xa levels, is measured 4 hours after injection. The overall follow-up duration is not specified.

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NCT04861103

Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)

Recruiting
PHASE4Ages 18+InterventionalPrevention
University of California, Irvine
~12 participants
Updated 2025-10-29 on ClinicalTrials.gov
What's tested:Lovenox

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Factor Xa levels
Measured over 4 hours after injection
Pregnancy, High Risk
Anticoagulants
1 sites across 1 states
California1
  • Afshan Hameed · PRINCIPAL_INVESTIGATOR · University of California, Irvine

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Eligibility criteria

Inclusion

Nulliparous or multiparous women with single intrauterine pregnancies who require therapeutic low molecular weight heparin during their pregnancy.
Participants must be age 18 or older.

Exclusion

Women with multiples.
Women less than age 18
History of Heparin Induced Thrombocytopenia (HIT)
Allergy to enoxaparin
  • Factor Xa levels4 hours after injection