Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout
This study is comparing two common ways to manage gout: one aims to lower your uric acid levels (using allopurinol, naproxen, and colchicine) to a specific target, and the other focuses on treating symptoms as they arise. Researchers want to see which approach is better for people with gout. You might be eligible if you are 18 to 90 years old, have a confirmed diagnosis of gout, and are a patient at a participating primary care practice. The study will measure how often gout flares happen over two years to see which treatment strategy is more effective. The current recruitment status is unclear.
- Study design
- This is a randomized, controlled multicenter study planning to enroll 650 participants. It compares two treatment strategies for gout.
- What's involved
- Participants in the 'treat-to-target' group will have blood draws every 4 weeks until their uric acid target is reached. The study will follow participants for two years.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for two years after starting the study.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout
At a glance
Conditions
Where it's being run
7 sites across 5 statesStudy leadership
- Hyon K Choi, MD, PhD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Frequency of gout flarebaseline to two years of follow up
number of gout flares occurring during two years of follow-up between the TTT-SU and TTASx groups