Epidural Stimulation for Locomotor and Bladder Function After Spinal Cord Injury

This study is looking at how epidural stimulation, combined with different types of training, might help people with acute spinal cord injuries improve their ability to stand, walk, and control their bladder. The training includes standing, stepping, and exercises to improve bladder capacity (how much urine it can hold) and voiding efficiency (how well it empties). Researchers want to see if these treatments can help you stand and walk better, and if your bladder can store and empty urine more effectively. You might be able to join if you are between 18 and 65 years old, have a non-progressive spinal cord injury between T1 and T10, cannot stand or step on your own, and have bladder problems due to your injury. The study plans to enroll 16 participants, but its current status is unclear.

Study design
This is an interventional study planning to enroll 16 participants. It is not specified if it is randomized or blinded.
What's involved
You would participate in training sessions for ambulation and bladder function. The primary outcomes will be measured after 80 sessions, which is about 3 months.
Compensation
Not stated in the trial record.
Follow-up
Your ambulation and bladder function will be measured after 80 sessions, which is approximately 3 months.

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NCT04879862

Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury

Recruiting
NAAges 18–65Interventional
Claudia Angeli
~16 participants
Updated 2026-05-04 on ClinicalTrials.gov
What's tested:Epidural stimulation + Stand TrainingEpidural stimulation + Step TrainingEpidural stimulation + Bladder Capacity TrainingEpidural stimulation + Bladder Voiding Efficiency Training

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Ambulation
Measured over 80 sessions, approximately 3 months
+1 more outcome measured
Spinal Cord Injuries
1 sites across 1 states
New Jersey1

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  • Ambulation80 sessions, approximately 3 months

    Ability to take independent steps

  • Bladder storage/voiding80 sessions, approximately 3 months

    voiding and/or residual volume (ml)