Twin Block, Pain Medications and Third Molar Extractions
This study is looking at ways to manage pain after wisdom tooth removal without relying heavily on opioid medications. Researchers are testing a local anesthetic nerve block called the Twin Block, which uses 2% lidocaine with 1:100,000 epinephrine (a common dental anesthetic). They will compare this to a placebo (sterile normal saline) given through the same Twin Block injection. The goal is to see if the Twin Block can reduce muscle pain after the procedure, lower overall pain scores, and decrease the amount of opioid pain medication you might need. You could be eligible if you are over 18, healthy, and need at least one lower wisdom tooth removed under sedation. The study aims to enroll 48 participants.
- Study design
- This interventional study plans to enroll 48 participants to compare the Twin Block local anesthetic with a placebo.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your pain will be measured 15 minutes after the injection and again one week later. Total opioid consumption will also be tracked for one week.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Twin Block, Pain Medications and Third Molar Extractions
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Gayathri Subramanian, PhD, DMD · PRINCIPAL_INVESTIGATOR · Rutgers School of Dental Medicine, Newark NJ
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Post-injection muscle pain15 minutes
NRS pain scores before and 15 min after Twin block administration on day after procedure
- Mean NRS pain scoreone week
Means NRS pain score by Day, comparing placebo and Twin block groups
- Total prescription opioid consumptionone week
Comparison of total prescription opioid consumption (mg) between placebo and Twin block groups