Back to search results

CorEvitas SPHERES Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD)

This is an observational study for people with Neuromyelitis Optica Spectrum Disorder (NMOSD), a rare, lifelong autoimmune disease that affects the brain and spinal cord. It aims to collect information on how NMOSD progresses over time, how different treatments work in the real world, and how the disease impacts your quality of life. You can join if you are 18 or older, have an NMOSD diagnosis, and are willing to share your personal information. The study is currently recruiting about 800 participants across North America. The main goal is to understand the disease's epidemiology (how it affects populations), how it presents, its natural course, how it's managed, and its outcomes over at least 10 years.

Study design
This is an observational study that plans to enroll about 800 participants. It is not testing a specific intervention but rather collecting information on NMOSD.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for a minimum of 10 years from the last patient enrolled.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04886492

CorEvitas SPHERES (Synergy of Prospective Health & Experimental Research for Emerging Solutions) Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD)

Enrolling by Invitation
Not specifiedAges 18+Observational
CorEvitas
~800 participants
Updated 2026-02-09 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
NMO epidemiology, presentation, natural history, management, and outcomes
Measured over A minimum of 10 years from last patient enrolled

Conditions

Neuromyelitis Optica Spectrum Disorder

Explore related trials

Neuromyelitis Optica

Where it's being run

1 sites across 1 states
Massachusetts1

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Exclusion

All serology types (APQ4 +/- and MOG +/-) are eligible to enroll in the registry given they meet the 2015 IPND diagnostic criteria.

What this trial measures

  • NMO epidemiology, presentation, natural history, management, and outcomesA minimum of 10 years from last patient enrolled

    The major clinical outcomes include an assessment of the epidemiology of NMO; to better understand the presentation, natural history, management and outcomes.