Motor Training for Infants With Cerebral Palsy

This study is testing a new motor intervention called "Let's Move" for infants who are at risk for cerebral palsy. The researchers want to see if this intervention is practical and well-received by families, and if it shows early signs of helping infants' motor development. You might be able to join if your infant is between 3 and 8 months old (corrected age) and has certain risk factors for cerebral palsy, such as specific findings on an MRI or ultrasound. Caregivers must also be fluent in English. The main goal is to measure changes in your infant's motor skills using a test called the Peabody Developmental Scales - Second Edition, both before and after the intervention, and again later. The current status of this study is unclear, and it plans to enroll 35 participants.

Study design: This is an interventional study, meaning participants will receive a specific treatment. It aims to enroll 35 participants.
What's involved: Participants will receive the Let's Move intervention weekly for 16 weeks, with sessions lasting 30-60 minutes. These sessions will alternate between clinic visits and home-based video telehealth appointments.
Compensation: Not stated in the trial record.
Follow-up: Your infant's motor skills will be assessed at baseline, after 16 weeks of intervention, and again at 28 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Motor Training for Infants With Cerebral Palsy

Recruiting

NAAges 3–8InterventionalTreatment

Children's Hospital Medical Center, Cincinnati

~35 participants

Updated 2025-09-25 on ClinicalTrials.gov

What's tested:Let's Move Motor Intervention

At a glance

Recruiting sites

1 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Change on Peabody Developmental Scales - Second Edition before and after intervention and follow-up

Measured over Baseline,16 weeks, 28 weeks

Conditions

Cerebral Palsy

Where it's being run

1 sites across 1 states

Ohio1

Study leadership

Karen Harpster, PhD, OTR/L · PRINCIPAL_INVESTIGATOR · Children's Hospital Medical Center, Cincinnati

Who to contact

Karen Harpster, PhD, OTR/L

[email protected]

513-803-3604

Email the study team

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Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

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Eligibility criteria

Inclusion

Age at enrollment: between 3-8 months corrected age

Caregivers fluent in English

Preterm infants with objectively defined severe diffuse white matter abnormality on MRI at term OR

High-risk infants (e.g., preterm, neonatal hypoxic-ischemic encephalopathy, perinatal stroke) with moderate-severe injury on structural MRI or cranial ultrasound (e.g., basal ganglia/thalamic signal intensity, cystic periventricular leukomalacia, encephalomalacia, large stroke, and/or severe intraventricular/periventricular hemorrhage) at around term-equivalent age or before Neonatal Intensive Care Unit discharge AND either:

"Absent" fidgety movements based on the Prechtl General Movement Assessment (GMA) between 3-4 months corrected age OR

A score of 56 or below on the Hammersmith Infant Neuromotor Examination (HINE) between 3-6 months corrected age (31)

Exclusion

Medical conditions that restrict active participation such as oxygen dependence

Infants with significant visual deficits defined by the inability to track an object horizontally

Living in a remote location prohibiting drives to the hospital every other week.

What this trial measures

Change on Peabody Developmental Scales - Second Edition before and after intervention and follow-upBaseline,16 weeks, 28 weeks
Motor test

Trialytics