Exciflex for Chronic Wound Therapy

This study is testing a new electronic bandage called exciflex for people with chronic wounds, especially those caused by poor blood flow (ischemic wounds). It aims to see if exciflex works better than standard care to help wounds heal. You might be eligible if you are a Veteran with a chronic ischemic wound, particularly if you have a spinal cord injury or diabetes and are receiving wound care. Researchers will measure wound size using special imaging techniques at each bandage change for up to six weeks to see how well the treatment is working. The study is currently unclear on its recruitment status.

Study design
This is a randomized study with two groups, involving 16 participants. You would have a 50% chance of receiving the exciflex bandage or standard care.
What's involved
Your wound will be digitally imaged, and infrared and laser speckle imaging will be performed at each bandage change for up to six weeks.
Compensation
Not stated in the trial record.
Follow-up
Your wound healing will be monitored for up to six weeks.

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NCT04887688

Exciflex Electroceutical Banadage for Chronic Wound Therapy

Recruiting
NAAges 18+InterventionalTreatment
VA Office of Research and Development
~16 participants
Updated 2026-08-10 on ClinicalTrials.gov
What's tested:exciflex

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Digital imaging
Measured over At each bandage change for up to 6 weeks
+2 more outcomes measured
Chronic Wound
Diabetes
Spinal Cord Injury
Ischemic Wound
1 sites across 1 states
Ohio1
  • Kath M. Bogie, PhD · PRINCIPAL_INVESTIGATOR · Louis Stokes VA Medical Center, Cleveland, OH

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Eligibility criteria

Inclusion

All participants with chronic wounds treated at LSCVAMC will be potentially eligible for the study
Primary target populations will include Veterans with SCI who are inpatients or residents of the on-site Long-Term Care Unit and Veterans with diabetes being followed by the Podiatry Service for wound care
Pregnancy
  • Digital imagingAt each bandage change for up to 6 weeks

    Quantify wound size (mm2 for surface area, mmm3 for volume). The outcomes measures of wound surface area \& wound volume are done by the investigators' 3D wound imaging camera that produces a digital output which includes both wound surface area (SA) \& wound volume. One is derived from the other, i.e. Wound volume = SA x average depth.

  • IR imagingAt each bandage change for up to 6 weeks

    Wound bed temperature (degrees C)

  • Laser Speckle imagingAt each bandage change for up to 6 weeks

    Wound region blood flow (blood perfusion using arbitrary units)