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Social Relationships and Aging in Transplant Survivors

This observational study is looking at how social relationships affect aging in people who have had a hematopoietic cell transplant (stem cell transplant). Researchers want to understand if social support, strain, or isolation are linked to how quickly someone ages, both physically and biologically. You could join if you are 18 or older, can read and speak English, and had a stem cell transplant within the last 100 days. The study will measure a cellular aging marker called p16 at 100 days and one year after your transplant to see how social factors might impact it. The study aims to enroll 110 participants.

Study design
This is an observational study, meaning researchers will collect information without giving any specific treatments. It plans to include 110 participants.
What's involved
You would provide blood samples and complete questionnaires at 100 days and one year after your transplant. Researchers will also review your medical records.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for one year after their transplant, with assessments at 100 days and one year.

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NCT04892823

Social Relationships and Accelerated Aging in Hematopoietic Cell Transplant Survivors

Recruiting
Not specifiedAges 18+Observational
Medical College of Wisconsin
~110 participants
Updated 2026-08-05 on ClinicalTrials.gov
What's tested:Biospecimen CollectionElectronic Health Record ReviewQuestionnaire Administration

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The number of participants with gene expression of cellular senescence marker p16.
Measured over Day 100 and 1 year post-transplant

Conditions

Hematopoietic and Lymphoid Cell Neoplasm

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Hematopoietic and Lymphoid Cell Neoplasm

Where it's being run

1 sites across 1 states
Wisconsin1

Study leadership

  • Kelly Rentscher, PhD · PRINCIPAL_INVESTIGATOR · Medical College of Wisconsin

Who to contact

Medical College of Wisconsin Cancer Center Clinical Trials Office
[email protected]
866-680-0505 · ext. 8900
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Aged 18 years and older who are competent to give their informed consent.
Ability to read, speak, and understand English.
Received a hematopoietic cell transplant within the previous 100 days.

Exclusion

Less then Aged 18 years and older who are competent to give their informed consent.
Cannot read, speak, and understand English.
Has not received a hematopoietic cell transplant within the previous 100 days.

What this trial measures

  • The number of participants with gene expression of cellular senescence marker p16.Day 100 and 1 year post-transplant

    This will be measured by mRNA/gene expression.