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Measuring Nitric Oxide with UV Light

This study is exploring a new, non-invasive way to measure S-nitrosothiols (SNOs) in the body. SNOs are important molecules that help control many body functions, but they are currently hard to measure accurately without invasive procedures. Researchers will use a special device called a Nitric Oxide Analyzer attached to your earlobe to get a baseline reading. Then, a low-intensity UV flashlight (Alonefire SV003 10W 365nm UV Flashlight) will be shined on your earlobe. The goal is to see how much nitric oxide changes during this UV light exposure. This study is open to healthy individuals, aged 1 day to 75 years, who are not smokers, pregnant, or have chronic skin conditions. The study is currently unclear on its recruitment status and plans to enroll 150 participants.

Study design
This interventional study aims to enroll 150 participants. It is not specified if the study is randomized or blinded.
What's involved
You will have a Nitric Oxide Analyzer attached to your earlobe to get a baseline reading. Then, a low-intensity UV flashlight will be shined on your earlobe for 10 minutes.
Compensation
Not stated in the trial record.
Follow-up
Nitric Oxide changes will be measured at 30 minutes after UV light exposure.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04903535

External Nitric Oxide Measurement Through SNO Degradation

Enrolling by Invitation
NAAges 1–75InterventionalBasic science
Indiana University
~150 participants
Updated 2026-02-09 on ClinicalTrials.gov
What's tested:Alonefire SV003 10W 365nm UV Flashlight

At a glance

Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Nitric Oxide during UV light exposure
Measured over 30 minutes

Conditions

Healthy
Unconscious

Explore related trials

Healthy VolunteersLoss of Consciousness

NCT04903535

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Riley Hospital for Children

    Indianapolis, Indianano site contact published

  • Wells Center for Pediatric Research

    Indianapolis, Indianano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Nadzeya Marozkina, PhD, MD · PRINCIPAL_INVESTIGATOR · Indiana University

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Adult males or females age ≥ 1 day and ≤ 75 years at time of enrollment

Exclusion

Subjects meeting the following criteria will be excluded:
Smokers.
Any chronic skin conditions.
Pregnant.
Subjects that are unable or unwilling to cooperate with specimen collection.
Subjects with diagnosis of any medical condition that in the investigator's opinion would make them unsuitable for study participation.
(for subjects ≥ 18) Subjects that lack the capacity to consent for themselves.

What this trial measures

  • Change in Nitric Oxide during UV light exposure30 minutes

    NO evolved during UV light exposure from the human ear lobe, hand or forehead.