This study is looking at new ways to help people with Heart Failure with Preserved Ejection Fraction (HFpEF), a condition where your heart pumps normally but is too stiff to fill properly. We are testing if Potassium Nitrate, a drug that may increase blood flow to muscles, can improve your ability to exercise. We are also testing a combination of Potassium Nitrate with Propionyl-L-Carnitine and Nicotinamide Riboside, which might also improve how your muscle cells use energy. You could be eligible if you are an adult, have NYHA Class II-III symptoms (meaning you have some limitations with physical activity), and your heart's pumping function is at least 50%. The main goal is to see if these treatments improve your endurance during exercise after 6 weeks.

Study design

This interventional study plans to enroll 53 participants to test different treatments for HFpEF.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint is measured at week 6, suggesting follow-up for at least that duration.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.