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Comparing Grafting Techniques for Gum Tissue Around Teeth and Implants

This study is comparing two surgical methods to improve the gum tissue around teeth and dental implants. Researchers are looking at a "Strip Free Gingival Graft (SGG) plus Acellular Dermal Matrix (ADM)" versus a "Free Gingival Graft (FGG)". The goal is to see which technique is better at increasing the amount and quality of keratinized tissue (the tough gum tissue that protects your teeth and implants). You might be able to join if you are at least 18 years old, speak English, and are a patient at the UAB Dental School with areas lacking this protective gum tissue. The study will measure the quality and quantity of this tissue for up to 12 months.

Study design
This is a randomized controlled trial comparing two surgical techniques. It plans to enroll 20 participants.
What's involved
You would undergo one of two surgical procedures. Your soft tissue will be evaluated from the start of the study up to 12 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 12 months after the procedure to assess the regenerated soft tissue.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04920136

Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix

Recruiting
NAAges 18–99InterventionalTreatment
University of Alabama at Birmingham
~20 participants
Updated 2026-07-22 on ClinicalTrials.gov
What's tested:Strip Free gingival graft (SGG) + Acellular Dermal Matrix graft (ADM)Free Gingival graft

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Quality of soft tissue regenerated
Measured over From baseline to 12 months
+1 more outcome measured

Conditions

Gingival Recession
Lack of Keratinized Attached Peri-implant Mucosa
Thin Gingiva

Explore related trials

Gingival RecessionHypoplasia of gingivaLack of Keratinized Attached Peri-implant Mucosa

Where it's being run

1 sites across 1 states
Alabama1

Who to contact

Hussein Basma, DDS, MS
[email protected]
2059344506
Email the study team

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Eligibility criteria

Inclusion

English speaking
At least 18 years old
Able to read and understand informed consent document
Patients with teeth/implants lacking keratinized tissue.
Must be a patient of the UAB Dental School
Presence of periodontally healthy, non-carious neighboring teeth, healthy implants or edentulous ridges on either side of the involved site(s)

Exclusion

Non-English speaking
Less than 18 years old
Smokers/tobacco users (\>10 cigarettes/day)
Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
Presence of active periodontal disease
Previous soft tissue grafting at the site(s) to be treated

What this trial measures

  • Quality of soft tissue regeneratedFrom baseline to 12 months

    Compare the change in soft tissue quality (attached or keratinized ) between two used soft tissue grafts by superimposing the before and after intraoral scans and the calculating using a software the difference of soft tissue gain between both scans in (mm)

  • Quantity of soft tissue regenerated (Width of Keratinized Tissue)From baseline to 12 months

    Using a periodontal probe , the width of keratinized tissue will be measured in (mm) and compared between two grafts used.