Reducing Opioid Mortality in Illinois (ROMI) Study

This study, called ROMI, is looking for ways to help people with opioid use disorder (OUD) who are leaving Illinois jails and prisons. It tests two approaches: one involves "Case Management and Peer Recovery," where you get support from a case manager and a peer coach to connect with treatment. The other approach, "Naloxone-Only," trains you on how to use naloxone (a medication that can reverse an opioid overdose) and provides you with a kit and information on local resources. The goal is to see which approach helps people engage with addiction treatment for at least 12 months. You might be able to join if you are at least 18 years old, live in a designated research area, and likely have OUD. The study is currently enrolling participants.

Study design
This is a randomized controlled trial, meaning participants are randomly assigned to one of the two intervention groups. The study plans to enroll 1500 individuals.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, addiction treatment engagement, is measured at 12 months.

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NCT04925427

Reducing Opioid Mortality in Illinois

Recruiting
NAAges 18+InterventionalSupportive care
University of Chicago
~1,500 participants
Updated 2024-02-21 on ClinicalTrials.gov
What's tested:Case Management and Peer RecoveryNaloxone-Only

At a glance

Recruiting sites
1 of 5 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Addiction treatment engagement
Measured over 12 months
Opioid Use
Opioid-use Disorder
5 sites across 1 states
Illinois5
  • Harold Pollack, PhD · PRINCIPAL_INVESTIGATOR · University of Chicago
  • Mai Pho, MD · PRINCIPAL_INVESTIGATOR · University of Chicago

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Eligibility criteria

Inclusion

Participants must be at least 18 years old
Reside in designated research site county or zip code
Satisfy criteria for likely OUD based upon nonmedical use of prescription opioids, heroin, or synthetic opioids.

Exclusion

Participants experiencing cognitive impairments that preclude informed consent.
Reside out of the service area.
Prior enrollment in a parallel JCOIN study.
  • Addiction treatment engagement12 months

    Number (%) of participants with two or more addiction treatment provider encounters within three months of study enrollment