Anakinra with Chemotherapy for Pancreatic Cancer
This study is looking at how well a drug called Anakinra works when combined with chemotherapy for pancreatic adenocarcinoma (a type of pancreatic cancer). Researchers want to see if adding Anakinra to standard chemotherapy (Nab-paclitaxel, gemcitabine, and cisplatin before surgery, and 5-Fluorouracil, oxaliplatin, and irinotecan after surgery) can help normalize a specific marker in the blood called CA19-9. This marker can indicate how well treatment is working. You can join if you are 18 or older and have been diagnosed with pancreatic adenocarcinoma. The study aims to enroll 24 participants and is currently unclear about its recruitment status.
- Study design
- This is an open-label, single-arm study, meaning all participants receive the same treatment and everyone knows what treatment is being given. It plans to enroll 24 participants.
- What's involved
- You would self-administer Anakinra twice a day, daily, starting on the first day of chemotherapy, with a 2-day break before surgery. You would also receive pre- and post-operative chemotherapy.
- Compensation
- Not stated in the trial record.
- Follow-up
- The main goal of the study is measured at 24 months, suggesting follow-up for at least that long.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Chemotherapy + Anakinra in Patients With Pancreatic Adenocarcinoma (PDAC)
At a glance
Conditions
NCT04926467
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Baylor University Medical Center, Charles A Sammons Cancer Center
Dallas, Texasstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- A. Scott Paulson, MD · PRINCIPAL_INVESTIGATOR · Charles A. Sammons Cancer Center/Texas Oncology
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- To determine the percentage of patients that have a normalization of CA19-9 after pre-op treatment with the combination of nab-paclitaxel (abraxane), gemcitabine, cisplatin and anakinra.24 months