Injections for Shoulder Arthritis Pain

This study is looking at how well different injections work for primary glenohumeral osteoarthritis (GHOA), which is arthritis in your shoulder joint. Researchers want to compare corticosteroid injections with platelet-rich plasma (PRP) injections to see which is better at reducing pain. These injections are commonly used to help with pain and potentially delay or prevent the need for shoulder surgery. You may be able to join if you are at least 18 years old, have been diagnosed with primary GHOA, and have a baseline pain level above 4 on a pain scale. The main goal is to measure your pain level 12 weeks after the injection. The current recruitment status is unclear, but the study plans to enroll 200 people.

Study design
This interventional study plans to enroll 200 participants who will be randomly assigned to receive either a corticosteroid injection or a platelet-rich plasma injection.
What's involved
If you join, you will receive one injection. The trial record does not specify other visits, procedures, or tests.
Compensation
Not stated in the trial record.
Follow-up
Your pain level will be measured 12 weeks after the injection.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04949087

Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)

Recruiting
NAAges 18+InterventionalTreatment
Rush University Medical Center
~200 participants
Updated 2026-02-17 on ClinicalTrials.gov
What's tested:Glenohumeral Injection

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Visual Analog Scale-Pain (VAS)
Measured over 12 weeks
Arthritis Shoulder

NCT04949087

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Rush University Medical Center

    Chicago, Illinoisstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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Eligibility criteria

Inclusion

Patient ≥18y.o. of age
Primary glenohumeral arthritis (bone on bone or near bone on bone) that has been previously diagnosed on radiographs and clinical evaluation.
Baseline pain level of VAS \>4

Exclusion

Secondary causes of arthritis (i.e. septic arthritis, rheumatoid arthritis, rotator cuff arthropathy, post-traumatic arthritis)
Ipsilateral shoulder surgery within 1 year
Any glenohumeral joint injection within 3 months
Allergy to lidocaine
Known pregnancy
Workers compensation case regarding shoulder
  • Visual Analog Scale-Pain (VAS)12 weeks

    Validated patient-reported metric scale of pain: no pain (0-4 mm), mild pain(5-44 mm), moderate pain (45-74 mm), and severe pain (75-100 mm)