Time Restricted Feeding, Muscle, and Metabolism Study

This study is looking at how time-restricted eating and protein supplements might help with overweight and obesity. Researchers want to understand how muscle mass affects appetite and energy intake. You might receive a whey protein supplement (a dietary supplement), a ketogenic aid (another dietary supplement), or be in a control group that only does time-restricted feeding. The main goal is to see how these interventions change your body composition (like how much fat and muscle you have) over 120 days. You can join if you are 25-50 years old, live in Northwest Arkansas, and have a BMI (Body Mass Index) over 25. The study is currently unclear on its recruitment status.

Study design
This is an interventional study with a planned enrollment of 90 participants. It is not specified if it is randomized or blinded.
What's involved
Body composition will be measured at the beginning and on the final day (day 120) of the intervention. Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Body composition is assessed at baseline and on the final day (day 120) of the intervention.

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NCT04949451

Time Restricted Feeding, Muscle, and Metabolism

Recruiting
NAAges 25–50InterventionalBasic science
University of Arkansas, Fayetteville
~90 participants
Updated 2025-08-26 on ClinicalTrials.gov
What's tested:Whey protein supplementKetogenic aidControl group - time restricted feeding only

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Body composition
Measured over Change is being assessed at baseline and final day (day 120) of the intervention.
Overweight
Obesity
1 sites across 1 states
Arkansas1

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Eligibility criteria

Inclusion

Resides in Northwest Arkansas
Age 25-50 years
BMI \> 25
All ethnicities
Female and male

Exclusion

Food allergies
Pregnant or breastfeeding
Dietary restrictions (e.g. vegetarian, vegan, etc.)
Trying to lose weight in last 3 months
Pre-existing health conditions related to obesity (e.g. cardiovascular disease, diabetes, hypertension)
Prescription medications related to heart disease or type 2 diabetes
Fear of needles
Smoker or vaping
Currently taking protein supplements or other nutritional supplements which may interfere with study outcomes
Consumes \>4 alcoholic beverages per week
  • Body compositionChange is being assessed at baseline and final day (day 120) of the intervention.

    Body composition measured using dual x-ray absorptiometry to determine the ration of lean/fat-free mass to fat mass.