Shear-wave Elastography for Diaphragm Muscle Activity

This study is looking at a new way to measure how well your diaphragm muscle (the main muscle used for breathing) is working. Researchers are using a special ultrasound called Shear-wave elastography to look at diaphragm muscle activity. They want to see how this measurement relates to other ways of testing breathing, like measuring pressure in your diaphragm and stimulating a nerve in your neck. This study is for healthy adult volunteers, both men and women, who are not pregnant and don't have lung conditions like COPD or asthma that need regular treatment. The main goal is to measure shear wave speed after 3 hours. The current recruitment status is unclear.

Study design
This is an interventional study with a planned enrollment of 24 healthy adult volunteers.
What's involved
You would undergo various respiratory muscle tests, including breathing efforts and nerve stimulation, along with Shear-wave elastography.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at 3 hours, suggesting a short follow-up period.

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NCT04959526

Shear-wave Elastography Compared to Respiratory Function Testing

Recruiting
NAAges 18+InterventionalBasic science
Mayo Clinic
~24 participants
Updated 2026-03-16 on ClinicalTrials.gov
What's tested:Shear-wave elastography

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Shear wave speed
Measured over 3 hours
Respiratory Function Loss
Respiratory Complication
1 sites across 1 states
Minnesota1
  • Carlos Matilla, MD, PhD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

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Eligibility criteria

Exclusion

Volunteers who are pregnant.
Volunteers with known pulmonary pathology (COPD, asthma requiring routine treatment).
  • Shear wave speed3 hours

    Elastography of the diaphragm muscle across various behaviors and conditions