Clarifying the Optimal Application of SLT Therapy Trial for Glaucoma and Ocular Hypertension
This study is looking at two ways to use Selective Laser Trabeculoplasty (SLT) for people with glaucoma and ocular hypertension (high pressure in the eye). Researchers want to see if using SLT at a low energy level works as well as the standard energy level. They also want to find out if having low energy SLT once a year can prevent or delay the need for daily eye drops better than waiting for the treatment to wear off before repeating it. You might be able to join if you are 18 or older, in good health, and have high-risk ocular hypertension or glaucoma. The study will measure how long the treatment works over 12 and 48 months. The current recruitment status is unclear, and the study plans to enroll 790 participants.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It aims to enroll 790 participants to compare Low Energy SLT and Standard Energy SLT.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 12 months and then again at 48 months to see how long the treatment is effective.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Clarifying the Optimal Application of SLT Therapy Trial
At a glance
Conditions
Where it's being run
29 sites across 17 statesStudy leadership
- Tony Realini, MD, MPH · STUDY_CHAIR · West Virginia University
- Goundappa K Balasubramani, PhD · PRINCIPAL_INVESTIGATOR · University of Pittsburgh
- Stephen Wisniewski, PhD · PRINCIPAL_INVESTIGATOR · University of Pittsburgh
Who to contact
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What this trial measures
- 12-month survival12 months
Survival of first SLT through Month 12
- 48-month survival48 months
At Month 12, subjects are randomized to repeat SLT either annually at low energy or PRN at standard energy. The proportion controlled with SLT alone at Month 48 will be compared between groups