Pancreatic Cancer Early Detection Consortium

This study, called the Pancreatic Cancer Early Detection (PRECEDE) Consortium, is looking into ways to find pancreatic cancer (PDAC) early and prevent it. Researchers are studying people who have a higher risk of pancreatic cancer, such as those with a family history of the disease or those with specific genetic changes (like in the ATM, BRCA1, BRCA2, CDKN2A, PALB2, or STK11 genes). The study aims to understand how these factors relate to developing pancreatic cancer over an average of six years. There are no specific interventions or drugs being tested; instead, researchers are collecting information and samples from participants to learn more about the disease. The study plans to include 20,000 participants between 18 and 90 years old.

Study design
This is an observational study, meaning researchers will collect information and samples without providing any specific treatments. It plans to include 20,000 participants.
What's involved
You would provide biosamples (like blood) every 6-12 months. Clinical data and outcomes will also be collected from your medical records.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed through study completion, which is an average of 6 years.

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NCT04970056

Pancreatic Cancer Early Detection Consortium

Recruiting
Not specifiedAges 18–90Observational
Arbor Research Collaborative for Health
~20,000 participants
Updated 2026-07-22 on ClinicalTrials.gov

At a glance

Recruiting sites
55 of 60 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Development of PDAC
Measured over Through study completion, an average of 6 years
Pancreas Cancer
Pancreas Cyst
Pancreatic Ductal Adenocarcinoma
Genetic Predisposition
60 sites across 33 states
California9
New York5
Florida3
Illinois3
Pennsylvania3
Virginia3
Spain3
Arizona2
  • Diane Simeone, MD · STUDY_CHAIR · UC San Diego Moores Cancer Center

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Do you actually qualify for this trial?

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Eligibility criteria

Exclusion

Individuals not meeting the criteria above.
  • Development of PDACThrough study completion, an average of 6 years

    Diagnosis of PDAC