Mobile Health Exercise for Older Adults with Myeloid Neoplasms

This study is for older adults (age 60 and above) with myeloid neoplasms (a type of cancer affecting blood cells) who are receiving outpatient cancer treatments. It's testing if a mobile app called GO-EXCAP Mobile App, which provides a walking and resistance exercise program, can improve physical function. Some participants will instead receive information about chemotherapy from an oncology nurse. The main goal is to see if the exercise app helps with physical function after 12 weeks. Researchers will also look at how the app affects fatigue, mood, and quality of life. The study is currently recruiting 170 participants.

Study design
This is a randomized controlled trial, meaning participants are randomly assigned to either the exercise app or the educational control group. It aims to enroll 170 older adults.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, physical function, is measured at 12 weeks.

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NCT04981821

A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms

Recruiting
NAAges 60+InterventionalSupportive care
University of Rochester
~170 participants
Updated 2026-07-15 on ClinicalTrials.gov
What's tested:GO-EXCAP Mobile AppBehavioral Placebo Control

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Difference between experimental and active comparator arms- Physical Function
Measured over 12 Weeks
Cancer
Myeloid Neoplasm
1 sites across 1 states
New York1
  • Kah Poh Loh · PRINCIPAL_INVESTIGATOR · University of Rochester

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Eligibility criteria

Inclusion

Age ≥60 years (conventional definition of older age in clinical trials of MN)
Have a diagnosis of MN
Planned for or receiving outpatient cancer-directed treatments (participants receiving consolidative or maintenance outpatient therapies after induction chemotherapy are allowed to enroll)
English speaking
Eastern Cooperative Oncology Group (ECOG) performance status of 0-3
No medical contraindications for exercise per oncologist
Able to walk 4 meters as part of Short Physical Performance Battery measured walk (with or without assistive device)
Able to provide informed consent

Exclusion

Physical, psychological, or social impairments that would interfere with subject's ability to participate in the study or participate in the intervention, as determined by the PI or the treating team
  • Difference between experimental and active comparator arms- Physical Function12 Weeks

    Changes in physical function measured using the Short Physical Performance Battery (SPPB) which an objective physical assessment evaluating lower extremity physical function (score ranges from 0-12; higher score indicates better physical function). It is comprised of 3 components: a four-meter walk, repeated chair stands and a balance test (the score for each component ranges from 0-4).