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Weight Loss Study for Young Stem Cell Transplant Patients

This study is testing a mobile health (mHealth) app called W8L2G to help young people (ages 13-30) who have had a stem cell transplant and are obese. The app uses ideas from addiction principles to help with weight loss, and you'll also work with coaches. The main goal is to see if the app helps reduce Body Mass Index (BMI) after 4 months. This is a small pilot study aiming to enroll 20 participants. You can join if you are between 13 and 30 years old, have had a stem cell transplant at least 100 days ago, and are classified as obese.

Study design
This is a pilot study with 20 participants. It is an interventional study, meaning participants will receive the W8L2G mobile health app and coaching.
What's involved
You will have an initial visit, followed by two in-clinic visits at 2 and 4 months. You will also have weekly phone calls and daily weekday texts for 4 months.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at 4 months, which is the conclusion of the study.

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NCT04997473

Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients

Recruiting
NAAges 13–30Interventional
University of California, Los Angeles
~20 participants
Updated 2026-01-28 on ClinicalTrials.gov
What's tested:W8L2G mobile health (mHealth) app

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
BMI
Measured over 4 months

Conditions

Obesity
Stem Cell Transplant

Explore related trials

Hematopoietic Cell TransplantationObesity

Where it's being run

1 sites across 1 states
California1

Study leadership

  • Theodore B Moore, MD · PRINCIPAL_INVESTIGATOR · UCLA Health

Who to contact

Belen Ramirez
[email protected]
3102670425
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients ≥ 13 and ≤ 30 years old with a history of HSCT of any type, at least 100 days post-transplant at initial consultation of the study, will be eligible for the study.
Both male and female patients will be eligible.
Patients must classify as obese, represented as Body mass index \[BMI\] ≥85th percentile for age and gender.
Patients must also be able to read English since the app intervention is only available in English form.

Exclusion

Patients who are ≤ 13 or ≥ 30 years old are not eligible for the study.
Patients who are \< 100 days post-transplant at initial consultation will not be eligible for the study, but may become eligible if they are \>100 days post-transplant at their next consultation that falls within the enrollment window.
Patients whose BMI does not fall under the obese category will be excluded.
No patients will be excluded for any specific underlying medical condition, but decisions will be made on a case by case basis if a patient's functioning is deemed to significantly interfere with intervention participation.

What this trial measures

  • BMI4 months

    To evaluate the effectiveness of an addiction-based weight loss intervention, embodied as a smartphone app with telephone coaching, on weight (weight and height will be combined to report BMI in kg/m\^2) outcomes of overweight and obese post HSCT adolescents and young adults.